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LS CancerDiag Ltd is committed to reducing cancer mortality rates with a simple and accurate diagnostic method for inherited MMR deficiency. The MMR deficiency is associated to Lynch syndrome, the world’s most common inherited cancer predisposition. Our vision is to make DiagMMR® the new global standard test for Lynch cancer syndrome diagnosis, and support the early detection of the disease even before tumors develop.
Lynch syndrome is the main cause of hereditary cancers with a broad spectrum of tumors, the most prominent being colorectal and endometrial cancers. With an estimated 1 in 300 people of the world’s population being affected by Lynch syndrome, there are millions of people under a highly increased risk for cancer.
Our groundbreaking DiagMMR® assay is an unique functional test that can be used for diagnosis of MMR deficiency i.e. Lynch syndrome (previously known as Hereditary NonPolyposis Colorectal Cancer; HNPCC).
Our mission is to enable an easy and accurate Lynch cancer syndrome detection or exclusion, provide actionable results, and help prevent cancer through an innovation that dramatically simplifies diagnostics of Lynch syndrome by delivering predictive, reliable and accurate testing.
Enable an easy and accurate Lynch cancer syndrome detection or exclusion
Make DiagMMR® the global standard test
for Lynch cancer syndrome diagnosis
Lynch syndrome is characterized by an inherited functional deficiency in the mismatch repair (MMR) process in cells. The genes encoding for MMR proteins involved in this process have been identified and studied for many years. Our founder and CEO Prof. Minna Nyström is an internationally distinguished expert in this field. Back in the 90s when she started to use sequencing as a novel method to enable disease causing mutation finding in the susceptibility genes, she already saw possible limitations in the method.
She realized that knowing the DNA sequence changes, while being useful information, would not reveal the actual malfunction of the encoded MMR proteins, unless it was possible to test for exactly that. So she set out to develop such a method. DiagMMR® is the result of many years of dedicated research to get to the point, where MMR functionality, and functional deficiency typical to Lynch syndrome, can be analyzed directly without the need of any underlying clinical data. It can therefore help medical professionals and patients alike, by providing actionable results and help answering questions that remained unanswered to this day.
This new method supports the trend and the need to combine existing data with new insights and data points to enable more personalized treatments and preventive measures in the fight against cancer.
LS CancerDiag is based in Finland and was founded as a
spin-off from the University of Helsinki.
Learn more about our team and the people
that make up LS CancerDiag.
LS CancerDiag has launched a funding round in collaboration with Springvest.
The company aims to raise €5.4M in capital to support the expansion into the United States and introduce DiagMMR® to the largest health care market in the world.
